Some programs may not be compatible with windows 10 but most should work. I have found that some programs fail to open after the upgrade and a simple repair or re-install should fix them. Remember if you have trouble finding your way around just press the “start” or “windows” button and type what you are looking for. If you have come here right after the upgrade you may still be missing drives and essential updates that will end up fixing your problem. Don’t forget to try restarting your computer every-so-often to apply the updates that have been installed.